Outcome Based Reporting: View the beta testing sites here

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Historically, IVF treatment results have been reported with a focus upon age as the primary differentiating factor in terms of expected outcome. However, there are well known and defined factors that affect IVF outcome in addition to the age of the egg provider and the type of procedure performed. The Outcome Based Reporting System (OBRS™) is a computerized IVF-specific data collection system that provides reliable IVF outcome data in real time. Results for conventional IVF (with the patient’s own eggs) are presented in separate categories by age, each of which is further divided into four (4) subgroups (A through D) based on relative Categories of Complexity using the following variables that are known to affect outcome:

 

  • The number of prior failed IVF attempts;
  • Ovarian reserve as measured by:

(1) FSH blood level on the 3rd day of the menstrual cycle,

(2) Follicular response of the ovaries to stimulation with specific dosages of gonadotropins, and

(3) Number of eggs recovered at retrieval; and

(4) Type of IVF procedure performed, e.g., fresh cycle using own eggs versus fresh cycle using ovum donor-derived eggs, and the use of thawed embryos for transfer (frozen embryo transfers- FET)

 

OBRS™ ensures accurate representation of all cases undergoing embryo transfer (the “denominator of outcome”) for statistical computation. The outcomes are updated every 3 months to ensure that all ongoing pregnancies (beyond the 1st trimester) are accurately represented. It is only through a process such as OBRS™ that it is possible, against the background of relevant demographic, clinical, and laboratory variables (that affect IVF outcome), to verifiably present statistics in a manner that permits reasonable case-to-case comparison without having to compare “apples with oranges”.

 

OBRS™ will be utilized by the participating ART program(s) with the requirement that only those IVF cases that have been fully registered/logged into the data collection system at the onset of ovarian stimulation with fertility agents will be eligible for inclusion. This requirement will ensure that the most important variable, namely accurate representation of all cases undertaken (the “denominator of outcome”), is available for statistical computation. A validated denominator, together with a validated outcome (the numerator), will permit proper computation of the pregnancy rate for each Category of Complexity in order to allow greater specificity, i.e., an “apples-to-apples” comparison of outcome data and thus, enhanced predictive value of the data.

 

There are 5 anonymous Beta Testing Sites (Clinics) currently testing the system using categories of complexity. You can view the outcome based IVF statistical pregnancy data here:

 

http://www.ivfstats.org/

 

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