Reproductive Immunology

4 years 6 months ago

A 1995 study evaluating the efficacy of intravenous immunoglobulin for treatment of individuals experiencing unexplained recurrent pregnancy loss.

4 years 6 months ago

Recently there has been recognition that implanting embryos engage in a “cross talk” allowing it to develop unhindered in the uterus rather than be rejected. The embryo, upon arrival in the uterus, relays its desire to enter into a “dialogue” with the endometrial immune system. What this might mean to implantation is discussed by Geoffrey Sher,M.D.

Graphis of words associated with immunology
4 years 6 months ago

The complexity of the immune system can be key in treating both implantation failure and pregnancy loss.

4 years 6 months ago

Until the last decade, there was little a couple could do if they suffered from recurrent pregnancy losses. Miscarriages that couldn't be attributed to chromosomal defects, hormonal problems or abnormalities of the uterus were labeled "unexplained," and couples would continue to get pregnant, only to suffer time and again as they lost their babies. New research, however, has provided information on the causes of the heretofore unexplained pregnancy losses allowing more effective treatment enabling women to carry their babies to term.

4 years 6 months ago

IVig (intravenous immunoglobulin) is an expensive treatment for both implantation failure as well as multiple miscarriages resulting from reproductive immunological complications. Here is a pre-treatment sample letter for medical necessity or a post treatment appeal for use of this very expensive medication.

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